Haemolytic Transfusion Reaction

🔑 Key Priorities

• Stop transfusion immediately

• Support circulation and prevent renal injury

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🧠 Team Actions

Role	Task
Team Leader	Direct clinical management and communication
Circulation	Stop transfusion, maintain IV access
Labs/Runner	Return product to lab, send repeat blood samples

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🧭 Management Algorithm

1. Stop transfusion and disconnect line

2. Maintain IV access and give fluid bolus (10–20 mL/kg)

3. Treat hypotension (vasopressors, adrenaline if shock)

4. Administer steroids (e.g. methylprednisolone 1–2mg/kg)

5. Start diuresis (e.g. frusemide ± mannitol)

6. Monitor for coagulopathy and treat with FFP/cryoprecipitate

7. Take repeat blood samples for group/crossmatch and labs

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🔄 Ideal Crisis Flow

    Haemolytic Transfusion Reaction
                ↓
      Stop Transfusion, Maintain Access
                ↓
    IV Fluids + Steroids + Diuretics + Vasopressors
                ↓
     Monitor Coagulation + Renal Parameters
                ↓
       Return Product, Repeat Group & Save