Anaphylaxis

🔑 Key Priorities

• Remove trigger

• Restore perfusion and airway protection

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🧠 Team Actions

Role	Task
Team Leader	Guide severity grading and escalation
Airway Manager	Secure airway early if required
Circulation	IV access, fluid bolus, prepare adrenaline

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🧭 Management Algorithm

1. Cease suspected trigger (drug, latex, chlorhexidine)

2. 100% O₂, stop volatile agent

3. Administer adrenaline:

   • Grade 2: 10–50 mcg IV boluses

   • Grade 3: 100–200 mcg IV boluses

   • Grade 4: 1mg IV as for cardiac arrest

4. Give fluid bolus: 10–20 mL/kg

5. Start adrenaline infusion if requiring multiple boluses

6. Add hydrocortisone 200mg ± antihistamines

7. Consider vasopressin, noradrenaline if refractory

8. Take serum tryptase samples at 1, 4, 24 hours

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🔄 Ideal Crisis Flow

            Suspected Anaphylaxis
                    ↓
         Cease Trigger, 100% O₂, Call Help
                    ↓
        Adrenaline Bolus ± Infusion + Fluids
                    ↓
      Escalate with Vasopressors if Refractory
                    ↓
        Secure Airway + ICU + Tryptase Samples