2023.1 Day 1 VIVA 8

Peri-operative Medicine

An 82 year old female has presented with a severely angulated distal radius fracture with median nerve paraesthesia, after slipping on a step outside the local pub this afternoon. The general surgeon indicates that urgent reduction of the fracture is required within 2 hours.

Past Medical History:

  • Rheumatoid Arthritis

  • Asthma

  • Hypertension

Pre- Operative ECG: Atrial Fibrillation at rate 70-80

Medications:

  • Prednisolone 5 mg daily

  • Candesartan 4 mg daily

  • Omeprazole 20 mg mane

  • Methotrexate – 20 mg weekly (for arthritis) Abatacept injection- 125 mg weekly (for arthritis)

  • Folic acid – daily

  • Ciclesonide 160mcg – 1 puff daily

  • Salbutamol PRN

How can this patient be further assessed prior to their procedure?

Major Issues are:

  • Severe Rheumatoid Arthritis (RA)

    • Airway concerns: Cervical spine instability, TMJ involvement, limited mouth opening.

    • Steroid dependency → risk of adrenal insufficiency.

  • Atrial Fibrillation (AF)

    • Rate-controlled at 70-80 bpm, but potential for perioperative destabilisation.

    • Is it new or longstanding? Identify triggers (pain, sepsis, hypoxia, electrolyte imbalance).

  • Asthma

    • Current severity? Recent exacerbations?

    • Steroid-dependent → higher risk of bronchospasm perioperatively.

  • Hypertension

    • Well-controlled? Check BP trends, medication compliance, volume status.

  • Mechanism of fall & fasting status

    • Did syncope contribute to the fall? Assess for underlying medical cause (e.g., arrhythmia, TIA).

    • Aspiration risk → recent meal/alcohol intake?

How would you assess this patient further prior to anaesthesia?

  • History:

    • RA symptoms: Severity, mobility, morning stiffness.

    • Asthma: Frequency of salbutamol use, any nocturnal symptoms.

    • AF history: When diagnosed? Rate vs rhythm control?

  • Examination:

    • Airway: Mouth opening, neck mobility (cervical spine stability).

    • Cardiovascular: BP, HR stability, signs of volume depletion.

    • Respiratory: Wheeze, oxygen saturation, peak expiratory flow (if possible).

  • Investigations:

    • ECG: AF rate, ischaemic changes.

    • Bloods: FBC, UECs, magnesium, calcium (electrolyte causes of AF).

    • CXR if concerns about aspiration or respiratory status.

How would you optimise the patient before proceeding with anaesthesia?
  • Pain relief: IV paracetamol + fentanyl (cautious dosing due to age/comorbidities).

  • Fluid resuscitation: If hypovolaemic, cautious IV fluid bolus (250-500 mL crystalloid).

  • Asthma: Ensure bronchodilator therapy (salbutamol MDI or nebuliser if needed).

  • AF: Correct electrolyte disturbances before considering rate control.

  • Steroid supplementation: Consider stress-dose hydrocortisone (50-100 mg IV) if concern for adrenal insufficiency.

What anaesthetic options would you consider for this procedure?

    • Regional anaesthesia (preferred if feasible):

      • Bier’s block (IV regional anaesthesia) – BUT caution if patient is intoxicated/uncooperative.

      • Ultrasound-guided brachial plexus block (axillary or supraclavicular approach).

    • General Anaesthesia (GA) considerations:

      • Aspiration risk: If recently eaten → RSI with modified doses.

      • Difficult airway risk: Plan for video laryngoscopy, awake fibreoptic if high risk.

      • Induction: Lower doses of propofol (e.g., 1 mg/kg) + fentanyl (25-50 mcg) + suxamethonium or rocuronium.

      • Maintenance: Sevoflurane or TIVA (if haemodynamically unstable).

Q: Would you proceed in the Emergency Department or take the patient to theatre?

  • In theatre if:

    • GA is required due to uncooperative patient.

    • Significant aspiration risk or need for advanced airway management.

    • Concerns about RA airway involvement requiring fibreoptic intubation.

  • In ED if:

    • Regional technique can be used successfully in a cooperative patient.

In PACU, the patient develops a HR of 124 bpm. What are your differentials?

  • Pain (most common cause).

  • Hypovolaemia (inadequate fluid resuscitation).

  • AF with rapid ventricular response (triggered by stress, pain, or hypoxia).

  • Hypoxia (bronchospasm, atelectasis).

  • Sepsis (if wound infection or aspiration occurred).

  • Electrolyte disturbance (hypokalaemia, hypomagnesaemia).

How would you assess and manage this tachycardia?
  • Immediate assessment:

    • Check full vitals (BP, SpO₂, temperature).

    • ECG: AF with RVR? Ischaemic changes? New arrhythmia?

    • Assess pain & administer adequate analgesia.

    • Consider fluid resuscitation (250–500 mL crystalloid bolus) if hypovolaemic.

  • If persistent AF with RVR (>120 bpm):

    • Correct electrolyte imbalances (replace K⁺/Mg²⁺).

    • Beta-blockers (if BP stable):

      • Metoprolol 2.5–5 mg IV slow push (titrate cautiously).

    • Diltiazem (if preferred over beta-blockers for AF control).

    • If haemodynamically unstable → urgent cardiology input +/- synchronised cardioversion.

Q: When would you consider safe discharge from PACU?

  • HR controlled (<100 bpm) and stable.

  • Pain well managed.

  • No worsening respiratory or neurological signs.

  • Plan for postoperative anticoagulation & AF follow-up if needed.

Bonus Question

What if the patient has ongoing pain despite initial interventions?
  • Multimodal analgesia:

    • Paracetamol, NSAIDs (if no contraindications), opioids cautiously.

    • Lidocaine patch or regional catheter for prolonged pain control.

  • Consider ketamine infusion for opioid-sparing effect if severe pain persists.

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